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Integrating Bio-control and Biostimulant Functions: Application Cases of Chitosan Oligosaccharide

Sep 01 , 2025

Against the backdrop of global agricultures green transition toward less fertilizer, fewer pesticides, and greater efficiency, chitosan oligosaccharide is emerging as one of the most promising new inputs, thanks to its dual value as both a biocontrol agent and a biostimulant. It can not only trigger plants own immune responses, helping them resist fungi, bacteria, and nematodes, but also enhance their tolerance and yield stability under heat, drought, and disease stress. As a result, chitosan oligosaccharide formulations are moving from laboratory trials into field-scale applications, showing vast market potential.

Market Significance and Potential of Chitosan Oligosaccharide

Aligned with Green Agriculture Policies:

With the global agro-input industry under increasing pressure to reduce pesticide use and strengthen residue control, chitosan oligosaccharide stands out as a naturally sourced functional molecule that is both safe and efficient. It fits perfectly into the pathway of sustainable and green agriculture.

Integration of Biocontrol and Nutritional Enhancement:

Unlike traditional products with a single function, chitosan oligosaccharides not only suppress diseases but also stimulate crop growth and improve quality. This dual role addresses farmerscore demand for lower input, higher output.

Versatile Application Scenarios:

From fruits and vegetables to bananas, grapes, and broad-acre crops, chitosan oligosaccharide has proven applications in disease management, stress resistance, and shelf-life extension. Its growing list of successful cases continues to drive stronger market acceptance.

Building on more than 20 years of expertise in biostimulant R&D and industrialization, Qingdao Seawin Biotech has developed Targeted Enzymatic Digestion of Chitosan Oligosaccharide Preparation Technology, launching high-activity chitosan oligosaccharides and formulation products. 


 


Application cases across different crops have demonstrated their positive effects in disease control and shelf-life extension. In practical use, such products have shown outstanding performance in suppressing fungal diseases and prolonging post-harvest freshness. 

Case 1: Control of Banana Fusarium Wilt

In the Philippines, a combination of PlantNurse + Seawinner Synergy (a Bacillus subtilis formulation) was tried for the management of banana Fusarium wilt. After determining the optimal dosage through plate assays, the treatment was applied in large-scale field trials. The results demonstrated remarkable disease suppression compared with the untreated control, showing strong potential for integrated management of one of the most destructive banana diseases.


                                                                                           Control                                                                      PlantNurse + Synergy

Case 2: Cabbage Sclerotinia Management

In Australia, foliar spraying of PlantNurse on cabbage effectively reduced Sclerotinia infection. Field observations revealed that the incidence in treated plots was only about one-tenth of the control group. The visual evidence highlights the significant role of chitosan oligosaccharide formulations in reducing fungal pressure on leafy vegetables.

 

Videohttps://youtu.be/etpSvmT04WA 

Case 3: Disease Control and Shelf-life Extension of Table Grapes

In Italy, PlantGuard was evaluated on table grape. Field results demonstrated its effectiveness in reducing disease incidence, improving leaf and bunch health, enhancing overall vineyard resilience, and extending post-harvest shelf life. These findings highlight PlantGuard’s strong potential as a sustainable solution for modern viticulture.

             

                                                                                                   Control                                                                          PlantNuard

           

                                                                                     PlantNuard+ IC 50                                                                      Chemical Treatment

 

                                                 10 days after harvest                                                                                                                         16 days after harvest

(IC is a natural extract product)

The result showed that the treatment with PlantGuard showed a significant enhancement of both shelf life and quality standards.

Conclusion about Chitosan Oligosaccharide 

Chitosan oligosaccharide has proven to be a breakthrough input that unites biocontrol and biostimulant functions in a single, safe, and efficient molecule. Its ability to stimulate plant immunity, suppress major diseases, enhance stress tolerance, and extend post-harvest shelf life positions it as a key enabler of sustainable agriculture. Backed by Qingdao Seawin Biotechs targeted enzymatic hydrolysis technology and extensive field validation acrossdifferent crops, chitosan oligosaccharide products are rapidly moving from research to large-scale adoption. With their strong alignment to global green agriculture policies and clear economic benefits for farmers, these products demonstrate vast market potential and are set to play an increasingly important role in the next generation of agricultural solutions


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